The Powerpuff Girls, A national treasure? The Powerpuff girls aired on November 18, 1998 in the Former United States of America, Created by craig mccracken and broadcasted on Cartoon Network the Show recived a movie aswell in 2002. The Show ended on march 15th 2005 with McCracken and Savino believing Six Seasons was enough and that the series ran its course despite Cartoon Network offering a 7th season.